Health Information System (HIS) Interoperability is a very popular topic among Network members and Digital Health Implementers. At the recent WAHO September Joint Annual HIS and IDSR Managers and Partners Meeting in Cape Verde, it was reported that DHIS 2 will be rolled out in over 20 West and Central Africa countries by 2019. The topic of interoperability of DHIS 2 with other HIS featured in many discussions including the need to address data sharing, comprehensive data reporting and other HIS efforts. Admittedly, there is still a lot for implementers to learn thus, our October Global Digital Health Network meeting featured four experts to share their experiences in HIS Interoperability. Over 70 people joined the discussion in Washington, DC and online last Friday as our presenters delved into the subject.